HORDB

ID: hor002587
Uniprot ID: A8Y1S8
Protein name: NLP-12
Gene name: nlp-12
Organism: Caenorhabditis briggsae
Family: NA
Source: Animal
Expression: NA
Disease: NA
Comments: NA
Taxonomy: Caenorhabditis (genus), Peloderinae (subfamily), Rhabditidae (family), Rhabditoidea (superfamily), Rhabditomorpha (infraorder), Rhabditina (suborder), Rhabditida (order), Chromadorea (class), Nematoda (phylum), Ecdysozoa, Protostomia, Bilateria, Eumetazoa, Metazoa (kingdom), Opisthokonta, Eukaryota (superkingdom), cellular organisms
GO MF: GO:0031739 cholecystokinin receptor binding
GO BP: GO:0007218 neuropeptide signaling pathway; GO:0060756 foraging behavior
GO CC: GO:0043005 neuron projection; GO:0043025 neuronal cell body

Sequence: TQSPTFDRQD
Length: 10(21-30)
Propeptide: MLRNSCVLVLLILVFVDVFATQSPTFDRQDRDYRPLQFGKRDGYRPLQFGKRDYRPLQFGKRSGGGSVVLEPIWEWQ
Signal peptide: MLRNSCVLVLLILVFVDVFA
Modification: NA
Glycosylation: NA
Mutagenesis: NA

Structure: (PDB_ID-from https://www.rcsb.org/; AlphaFold_DB_ID-from https://alphafold.ebi.ac.uk/; hordbxxxxxx_AF2.pdb was predicted structure by AlphaFold2; hordbxxxxxx_ESM.pdb was predicted structure by ESMFold)

hor002587_AF2.pdb

hor002587_ESM.pdb

Mass:	135493	Formula:	C49H75N15O20
Absent amino acids:	ACEGHIKLMNVWY	Common amino acids:	DQT
pI:	4.11	Basic residues:	1
Polar residues:	3	Hydrophobic residues:	1
Hydrophobicity:	-195	Boman Index:	-4900
Half-Life:	7.2 hour	Half-Life Yeast:	>20 hour
Half-Life E.Coli:	>10 hour	Aliphatic Index	0
Instability Index:	14500	Extinction Coefficient cystines:	0
Absorbance 280nm:	0

PubMed ID: 18760316
Title: Comparative Peptidomics of Caenorhabditis Elegans Versus C. Briggsae by LC-MALDI-TOF MS